SciMetrika Scope assisted The Food & Drug Administration’s (FDA) Center for Biologics Evaluation and Research (CBER) with a 12 month project to develop a user-friendly statistical tool to study the presence of various bias parameters often found in observational data. The resulting web-based tool allows the user to input either record level or summary level data, choose the necessary study design, as well as multiple bias parameters. The tool then estimates bias in the data and provide point estimates and simulation intervals that account for both random, as well as systematic error, in the data.